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Estudo Piroctona Olamina < ANT / SEG >   [1 DE 3]


An in vivo procedure to evaluate antifungal agents on Malassezia pachydermatis in dogs: example with a piroctone olamine containing shampoo.

Abstract:

Objective:

  • The first objective of the present study was to develop an in vivo procedure as a possible model to evaluate the activity of topical antifungal agents against Malassezia pachydermatis.
  • The second objective was to apply this procedure to assess the antifungal properties of a shampoo containing piroctone olamine.

Analysis of variance showed a significant interaction effect between treatment and time at the left ear site (P < 0.01). The antifungal effect was maintained at least 4 days.

Conclusion:

The three sites chosen, ear canals and ventral neck, in groups of healthy dogs, can be used to evaluate the evolution of resident populations of Malassezia pachydermatis. The results of this study indicated also an unexpected prolonged antifungal effect obtained with a shampoo containing piroctone olamine that could be of interest when Malassezia overgrowth is observed in dogs.


Bibliografia:

P. Bourdeau, P. Blumstein, A.M. Marchand, L. Gardey, P. Jasmin and H. Gatto Unité de parasitologie–dermatologie–mycologie, école vétérinaire de Nantes, Atlanpole-La-Chantrerie, 44307 Nantes, France.

PUB.: 31-07-2012

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